Computational Chemist

Date: 27 Oct 2025

Location:

Bangalore, KA, IN, 560099

Division: Discovery Services

Job Description

Designation: Computational Chemist

Location: Bangalore

Department: Computational & Data Sciences

About Syngene

Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development, and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods, and specialty chemical industries worldwide. Syngene’s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA, and Herbalife. Its innovative culture is driven by the passion of its 4240-strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market, and lower the cost of innovation.

Job Purpose

To support drug discovery and material science projects by applying computational modeling, cheminformatics, QSAR/QSPR modeling, and data science techniques.

Key Responsibilities

• Apply cheminformatics approaches to analyze and interpret chemical and biological data.
• Implement QSAR/QSPR modeling techniques to predict molecular properties and enhance compound selection.
• Support the design and optimization of small and large molecules using various structure & ligand-based approaches.
• Utilize data science techniques, including machine learning, to derive insights from computational chemistry datasets.
• Prepare and submit reports in the relevant format and contribute to design sessions within the team.
• Provide support to the computational tool/workflow development.
  
  

Educational Qualification

• Master’s degree in Computational Chemistry, Organic Chemistry, Pharmacy, Biotechnology, Life Sciences, or a related field with experience in computational techniques for drug discovery.
  
  

Technical/Functional Skills

• Strong understanding of computational techniques relevant to drug discovery and material science.
• Experience with modeling tools such as Schrodinger (Maestro, Bioluminate, Materials Science), MOE, ICM, Cresset, KNIME, and Pipeline Pilot.
• Expertise in QSAR/QSPR modeling, cheminformatics, and data science approaches in drug discovery.
• Proficiency in molecular dynamics simulations, quantum chemistry, shape and electrostatic comparison, homology modeling, docking, and pharmacophore modeling.
• Familiarity with high-performance computing environments, Linux-based clusters, and GPU systems.
• Knowledge of Python programming is an advantage.
  
  

Experience

• 1-2 years of experience in drug discovery, medicinal chemistry, or computational modeling.
• Interest in acquiring knowledge and applying innovative techniques to advance medicinal chemistry and material science projects.
  
  

Behavioural Skills

• Ability to work in a multidisciplinary team with excellent interpersonal skills.
• Strong analytical and problem-solving skills with a proactive approach to challenges.
• Effective communication and presentation skills to convey complex scientific information clearly.
• Ability to adapt to dynamic project requirements and work independently or collaboratively.
  
  

Equal Opportunity Employer

Syngene is committed to providing equal employment opportunities (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. Additionally, Syngene will provide reasonable accommodations for qualified individuals with disabilities.